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Index » Regional/Local » USA/Canada » Health Care Page: Previous  1, 2, 3, ... 264, 265, 266  Next
Post to this Topic
Red_Dragon

Red_Dragon Avatar



Posted: Apr 17, 2019 - 4:09pm


miamizsun

miamizsun Avatar

Location: (3261.3 Miles SE of RP)
Gender: Male


Posted: Apr 17, 2019 - 3:26pm

after losing my grandmother to alzheimer’s disease i'd like to see others spared...

Senolytics Show Promise Against Alzheimer’s in Mice

For the past quarter century, scientists battled Alzheimer’s disease under a single guiding principle: that protein clumps—beta-amyloid—deposited outside sensitive brain cells gradually damage neuronal functions and trigger memory loss. The solution seems simple: remove junk amyloid, protect the brain.

They could be completely wrong.

Last month, Alzheimer’s disease defeated another promising near-market drug that tried to prevent or remove amyloid deposits, adding to the disease’s therapeutic “graveyard of dreams.” Although the drug removed toxic amyloid, the patients didn’t get better. The failure is once again spurring scientists to confront an uncomfortable truth: targeting amyloid clumps when patients already show memory symptoms doesn’t work. Wiping out soluble amyloid—fragments of proteins before they aggregate into junk—also dead ends.

It’s time to think outside the box.

Last week in Nature Neuroscience, Dr. Mark Mattson’s team at the National Institute on Aging Intramural Research Program added substantial proof that senolytics, the golden child of anti-aging drugs, rescue memory loss in Alzheimer’s disease, at least in mice genetically engineered to accumulate amyloid clumps in their brains.

more


Red_Dragon

Red_Dragon Avatar



Posted: Apr 17, 2019 - 8:04am

 cc_rider wrote:
Oh, a little word of caution about those so-called 'stand-alone emergency rooms' popping up everywhere. It's a racket. I know, you're shocked.

They are not 'Urgent Care' clinics like Minute Clinic or whatever. Those are great for colds, flu, etc.  These 'emergency rooms' are equipped and staffed like, well, an emergency room. Sounds good so far, right? Well, all that really means is they can charge emergency room rates! And it's not usually covered by insurance or Medi-anything. It's a racket designed to gouge people when they're desperate.

If you're seriously injured, the ambulance will not take you to one of those, it'll go to a real emergency room affiliated with a hospital system. That is, until these 'emergency rooms' get into the ambulance business, which I expect any day now...
c.

 
The oncology practice where P's was treated was bought by a hospital group. They made a bunch of upgrades to the facility that resulted in it actually being re-classified as a hospital. This enabled them to charge hospital rates. Her doc bailed after a few months and started his own practice.


cc_rider

cc_rider Avatar

Location: Bastrop
Gender: Male


Posted: Apr 17, 2019 - 7:46am

Oh, a little word of caution about those so-called 'stand-alone emergency rooms' popping up everywhere. It's a racket. I know, you're shocked.

They are not 'Urgent Care' clinics like Minute Clinic or whatever. Those are great for colds, flu, etc.  These 'emergency rooms' are equipped and staffed like, well, an emergency room. Sounds good so far, right? Well, all that really means is they can charge emergency room rates! And it's not usually covered by insurance or Medi-anything. It's a racket designed to gouge people when they're desperate.

If you're seriously injured, the ambulance will not take you to one of those, it'll go to a real emergency room affiliated with a hospital system. That is, until these 'emergency rooms' get into the ambulance business, which I expect any day now...
c.
miamizsun

miamizsun Avatar

Location: (3261.3 Miles SE of RP)
Gender: Male


Posted: Apr 17, 2019 - 5:57am

interesting updates on some heath sciences (plus a lot of other good stuff too)



miamizsun

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Location: (3261.3 Miles SE of RP)
Gender: Male


Posted: Apr 11, 2019 - 3:02pm

fantastic animation  



miamizsun

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Location: (3261.3 Miles SE of RP)
Gender: Male


Posted: Mar 27, 2019 - 9:12am

 kcar wrote:

 
 
This is very cool but I'm not sure that as this therapy in current form will ever offer affordable treatment to the general population. This therapy as I understand it requires analysis of a tumor's genetic code and pinpointing genetic vulnerabilities that, if attacked by T-cells or other agents of the immune system, would cause tumor cells to die. You also have to genetically modify T-cells to attack the tumor's genetic vulnerabilities—and you have to do that on a massive scale. From what I've read, you have to create a replacement number of modified T-cells and then wipe out the patient's immune system through chemo or radiation. You then introduce the modified T-cells so that they can attack the tumor cells. Even then this approach is applicable in about 30-40% of cancer cases.
 
Right now AFAIK this approach still cannot be used on solid tumors although researchers are trying to adapt it for such cases. I came across an article about this treatment in technologyreview.com around 3:30 am one night and spent the next 90 minutes trying to get a quick grasp of it with links to more technical articles for an email to send to my brother, whose wife was dealing with a rare and aggressive solid-tumor cancer in advanced stage. He talked to his wife's oncologist, who felt that the treatment couldn't help Catherine in part because solid tumors often have more than one genetic code in their mass, thus requiring a search for more than one set of vulnerabilities. Solid tumors also are effective at resisting penetration by therapeutic agents.
 
This therapy is very expensive and dangerous even if the patient is a good candidate. I don't know how you can create a relatively inexpensive and safe way of wiping out people's immune systems. Hopefully cancer research can find a less destructive and dangerous way of genetically altering people's T-cells.


 

that gadget is more of a quick diagnostic tool

here's another article that shines a little light on potential use(s)

The device could make genetic testing easier and more accessible.

Standardized Testing

To help make genetic screening easier and more accessible, scientists built a handheld device that uses CRISPR gene-editing technology to scan for mutations much more easily than existing labs can.

The device, which Keck Graduate Institute bioengineer Kiana Aran told Futurism looks a bit like a blood glucose monitor, can analyze a purified DNA sample for signs of Duchenne Muscular Dystrophy in a matter of 15 minutes — a major improvement compared to conventional wait times of several weeks.




kurtster

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Location: drifting
Gender: Male


Posted: Mar 26, 2019 - 1:12pm

 Lazy8 wrote:
Requires (free) registration.

Eye Exam Detects Signs of Alzheimer's Disease

By Linda Carroll
March 13, 2019
(Reuters Health) - Using an ultrasensitive scanning technique, researchers can detect signs of Alzheimer's disease in the tiny blood vessels at the back of the eye, according to a new report.

Duke University researchers found that these small retinal blood vessels were altered in patients with Alzheimer's disease, but in not in those with mild cognitive impairment (MCI) or those with no signs of mental decline.

"Among the folks who had Alzheimer's there was a significant reduction in the density of the blood vessels in the superficial layer of the retina compared to controls and those with mild cognitive impairment," said Dr. Dilraj Grewal, an associate professor of ophthalmology at the Duke Eye Center. "We also found a reduction in the thickness of (of a specific layer of the retina) in Alzheimer's patients compared to controls and those with mild cognitive impairment."

The findings were reported March 11 online in Ophthalmology Retina, a publication of the American Academy of Ophthalmology.


 
This is really cool.  The eye is hard wired directly to the brain and thus reveals many clues to our physical condition.  The eye works in both directions.  It is not an input only device.

Lazy8

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Location: The Gallatin Valley of Montana
Gender: Male


Posted: Mar 26, 2019 - 12:59pm

Requires (free) registration.

Eye Exam Detects Signs of Alzheimer's Disease

By Linda Carroll
March 13, 2019
(Reuters Health) - Using an ultrasensitive scanning technique, researchers can detect signs of Alzheimer's disease in the tiny blood vessels at the back of the eye, according to a new report.

Duke University researchers found that these small retinal blood vessels were altered in patients with Alzheimer's disease, but in not in those with mild cognitive impairment (MCI) or those with no signs of mental decline.

"Among the folks who had Alzheimer's there was a significant reduction in the density of the blood vessels in the superficial layer of the retina compared to controls and those with mild cognitive impairment," said Dr. Dilraj Grewal, an associate professor of ophthalmology at the Duke Eye Center. "We also found a reduction in the thickness of (of a specific layer of the retina) in Alzheimer's patients compared to controls and those with mild cognitive impairment."

The findings were reported March 11 online in Ophthalmology Retina, a publication of the American Academy of Ophthalmology.

pigtail

pigtail Avatar

Location: Southern California
Gender: Female


Posted: Mar 26, 2019 - 9:37am



 Isabeau wrote:


 buzz wrote:

wouldnt you heart rate and blood pressure vary according to whether you are having a hard time or an easy time? walked or ran to the bathroom? how smart is this toilet? can it be hacked? 
{#Ask}
 inquiring minds want to know. and so do i. 
{#Stupid}
 
 

Nope. Nada. No Way. Don't need to find me pucker on celebrityanuses.com  

 

If only Elvis were still alive.  He coulda been saved!
kcar

kcar Avatar



Posted: Mar 25, 2019 - 9:52pm

 miamizsun wrote:
the road to diagnosis at stage zero?

fast and near free?

let's hope so

Nanosens CRISPR-Chip video from Nanosens Innovations Inc. on Vimeo.



 
 
 
This is very cool but I'm not sure that as this therapy in current form will ever offer affordable treatment to the general population. This therapy as I understand it requires analysis of a tumor's genetic code and pinpointing genetic vulnerabilities that, if attacked by T-cells or other agents of the immune system, would cause tumor cells to die. You also have to genetically modify T-cells to attack the tumor's genetic vulnerabilities—and you have to do that on a massive scale. From what I've read, you have to create a replacement number of modified T-cells and then wipe out the patient's immune system through chemo or radiation. You then introduce the modified T-cells so that they can attack the tumor cells. Even then this approach is applicable in about 30-40% of cancer cases.
 
Right now AFAIK this approach still cannot be used on solid tumors although researchers are trying to adapt it for such cases. I came across an article about this treatment in technologyreview.com around 3:30 am one night and spent the next 90 minutes trying to get a quick grasp of it with links to more technical articles for an email to send to my brother, whose wife was dealing with a rare and aggressive solid-tumor cancer in advanced stage. He talked to his wife's oncologist, who felt that the treatment couldn't help Catherine in part because solid tumors often have more than one genetic code in their mass, thus requiring a search for more than one set of vulnerabilities. Solid tumors also are effective at resisting penetration by therapeutic agents.
 
This therapy is very expensive and dangerous even if the patient is a good candidate. I don't know how you can create a relatively inexpensive and safe way of wiping out people's immune systems. Hopefully cancer research can find a less destructive and dangerous way of genetically altering people's T-cells.

miamizsun

miamizsun Avatar

Location: (3261.3 Miles SE of RP)
Gender: Male


Posted: Mar 25, 2019 - 11:15am

the road to diagnosis at stage zero?

fast and near free?

let's hope so

Nanosens CRISPR-Chip video from Nanosens Innovations Inc. on Vimeo.


miamizsun

miamizsun Avatar

Location: (3261.3 Miles SE of RP)
Gender: Male


Posted: Feb 25, 2019 - 4:22am

i like where this is going

Watch genetically modified T-cells kill cancer cells


haresfur

haresfur Avatar

Location: The Golden Triangle
Gender: Male


Posted: Feb 6, 2019 - 3:17pm



 Isabeau wrote:


 buzz wrote:

wouldnt you heart rate and blood pressure vary according to whether you are having a hard time or an easy time? walked or ran to the bathroom? how smart is this toilet? can it be hacked? 
{#Ask}
 inquiring minds want to know. and so do i. 
{#Stupid}
 
 

Nope. Nada. No Way. Don't need to find me pucker on celebrityanuses.com  

 


Isabeau

Isabeau Avatar

Location: sou' tex
Gender: Female


Posted: Feb 6, 2019 - 2:43pm



 buzz wrote:

wouldnt you heart rate and blood pressure vary according to whether you are having a hard time or an easy time? walked or ran to the bathroom? how smart is this toilet? can it be hacked? 
{#Ask}
 inquiring minds want to know. and so do i. 
{#Stupid}
 
 

Nope. Nada. No Way. Don't need to find me pucker on celebrityanuses.com  
buzz

buzz Avatar

Location: up the boohai


Posted: Feb 5, 2019 - 3:40pm

 miamizsun wrote:
because someone has to give a poop...

Monitoring Heart Health, One Toilet Seat at a Time

This smart seat keeps tabs on your heart while you take care of business



Time and again, studies show that people are not good at consistently taking medication, following health care plans, or regularly recording health information, even when our doctor tells us to. 

And that’s a big problem in health care. In fact, the World Health Organization says that getting people to adhere to medical interventions could have a greater impact on world health than any specific medical treatment. 

Now, a team at the Rochester Institute of Technology (RIT) in New York has come up with a clever way to get patients with heart failure to track their heart health—let a toilet do it for them. 

Sensors in a new battery-powered, cloud-connected toilet seat track blood pressure, blood oxygen levels, and other heart data as accurately as hospital-grade monitoring equipment in a small group of patients, according to a study in the January issue of the journal JMIR mHealth and uHealth.

The idea of a “smart toilet” isn’t new—Google has a patent on a health-tracking toilet and Japanese manufacturers Toto and Matsushita (now part of Panasonic) have each developed Wi-Fi–connected toilets—but most health-related toilet technologies focus on urine and stool analysis inside the bowl, rather than tracking vital signs using sensors in the seat.



 
wouldnt you heart rate and blood pressure vary according to whether you are having a hard time or an easy time? walked or ran to the bathroom? how smart is this toilet? can it be hacked? 
{#Ask} inquiring minds want to know. and so do i. {#Stupid} 
miamizsun

miamizsun Avatar

Location: (3261.3 Miles SE of RP)
Gender: Male


Posted: Feb 5, 2019 - 3:13pm

because someone has to give a poop...

Monitoring Heart Health, One Toilet Seat at a Time

This smart seat keeps tabs on your heart while you take care of business



Time and again, studies show that people are not good at consistently taking medication, following health care plans, or regularly recording health information, even when our doctor tells us to. 

And that’s a big problem in health care. In fact, the World Health Organization says that getting people to adhere to medical interventions could have a greater impact on world health than any specific medical treatment. 

Now, a team at the Rochester Institute of Technology (RIT) in New York has come up with a clever way to get patients with heart failure to track their heart health—let a toilet do it for them. 

Sensors in a new battery-powered, cloud-connected toilet seat track blood pressure, blood oxygen levels, and other heart data as accurately as hospital-grade monitoring equipment in a small group of patients, according to a study in the January issue of the journal JMIR mHealth and uHealth.

The idea of a “smart toilet” isn’t new—Google has a patent on a health-tracking toilet and Japanese manufacturers Toto and Matsushita (now part of Panasonic) have each developed Wi-Fi–connected toilets—but most health-related toilet technologies focus on urine and stool analysis inside the bowl, rather than tracking vital signs using sensors in the seat.


miamizsun

miamizsun Avatar

Location: (3261.3 Miles SE of RP)
Gender: Male


Posted: Feb 5, 2019 - 4:16am



 Steely_D wrote:


 miamizsun wrote:
here's a six part series of visualizations...

 

I think the next healthcare giant begins their care with "Everyone gets their healthcare through video visits or telephone appointments by default - and now let's define those situations that are exceptions to that baseline."

So many people just have a quick question about a rash or a swelling or a medication or a lab result. In antiquated Fee-for-service medicine, the doctor made money every time the patient had to come in.

In future, the docs should be salaried like at Kaiser Permanente, and then their goal isn't to drive revenue via labs or visits, but to simply deliver high quality health care. That's done with a national health insurance system (which eliminates the separate VA, Occ Med, and the County systems - think of the savings) that covers all citizens.

That decreases unnecessary ER visits for non-emergent problems, encourages people to get help sooner rather than later - returning them to or keeping them on the job better.

Folks ask me how to fix the system. I'm not kidding when I say nuke it from orbit. So, although I don't care much for Kamala Harris yet, I appreciate her willingness to say the same. Healthcare for all? That would ruin the insurance system! Her response was basically: "so?"
 

there's the science, which is really making great strides (digitizing biology is very exciting to say the least)

also according to SU Exponential Medicine, some of the government/FDA are finally coming around

they realize that other countries are science friendly and that development and capture, esp IP will happen elsewhere

my concern is that the distribution/availability will be leveraged by double-speak politicians for special interests/groups

i don't have a lot of faith in harris, she seems very willing to change positions if it benefits her brand

Steely_D

Steely_D Avatar

Location: Biscayne Bay
Gender: Male


Posted: Feb 1, 2019 - 9:16pm



 black321 wrote:

Kaiser and the HMO model was an initial failure in many regards, as patients were denied or delayed life saving care. 

 ————

I think it takes people a while to figure out that giving bad care and getting bad press and even getting sued is ultimately more expensive than just doing it right. Despite that bit of common sense, I've met a lot of lazy, shiftless docs and I'm sure there are similar folks in all levels of administration and patient care.

And, some people just have rotten ideas that nearly bankrupt the company, like the guy that was running the doc portion of KP in the late 80s. Showing him the door and bringing in the brilliant Dr. Robbie Pearl literally saved the company. Those next three decades were the Golden Years.

It took a while to figure out the right business model as KP blazed a new trail. For instance: referring people out for sleep studies was costing the company a lot of money. So they bought the sleep lab and brought all the costs internally. Or, KP owns a bunch of MRI machines, so lets run them 6am-10pm 365 days and prevent delays in diagnosis or unnecessary hospitals stays.

What medical groups haven't learned fully yet (but KP is moving that way, intentionally) is that hospitals have to fully work, doing everything, seven days a week - not just M-F. If someone's admitted on Saturday morning, letting them sit in a hospital bed until Monday to see the specialist or get the nuclear study done is an extremely expensive and completely unnecessary waste of time (as well as a massive inconvenience to the patient and their family).

So, things change. You learn from the past, shuffle things around, and see if it's getting better. It's good to know the past - but better to know how things stand right now.
black321

black321 Avatar

Location: An earth without maps
Gender: Male


Posted: Feb 1, 2019 - 6:20am



 Steely_D wrote:

I think the next healthcare giant begins their care with "Everyone gets their healthcare through video visits or telephone appointments by default - and now let's define those situations that are exceptions to that baseline."

So many people just have a quick question about a rash or a swelling or a medication or a lab result. In antiquated Fee-for-service medicine, the doctor made money every time the patient had to come in.

In future, the docs should be salaried like at Kaiser Permanente, and then their goal isn't to drive revenue via labs or visits, but to simply deliver high quality health care. That's done with a national health insurance system (which eliminates the separate VA, Occ Med, and the County systems - think of the savings) that covers all citizens.

That decreases unnecessary ER visits for non-emergent problems, encourages people to get help sooner rather than later - returning them to or keeping them on the job better.

Folks ask me how to fix the system. I'm not kidding when I say nuke it from orbit. So, although I don't care much for Kamala Harris yet, I appreciate her willingness to say the same. Healthcare for all? That would ruin the insurance system! Her response was basically: "so?"
 
Kaiser and the HMO model was an initial failure in many regards, as patients were denied or delayed life saving care.  They have come a long way over the past 20-30 years, and the model could be just what our system needs.  Create a single payer model, with care provided by private HMO style organizations.  We already spend 18%-19% of GDP on healthcare, so we know the costs.  Provide vouchers to all citizens for them to obtain coverage from an HMO style organization.  And you are right, having everyone in the insured pool will help lower costs, by avoiding unnecessary expensive emergency procedures, that could be handled effectively with pharmaceuticals, the cheapest and most effective form of healthcare (contrary to popular belief, drug spending is not rising exponentially, in fact only in the low single digits).  Improved drug adherence overall will lower costs, as will new tech.  


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