my first hand experiences with the VA healthcare system is one of frustration and wasted time. We have a brand new facility here and a revolving door of practitioners. All those promises. All the money drops. Hello? Gladhanders and politicians? Are you there? Save a couple of bucks and just implement a voucher system so we can skip the facade? Please. The building is beautiful. There are people in there trying to do a good job. The system however...overburdened and woefully inefficient at the cost of quality of life.
TOPIC OF POSTING: HEATING PAD ADVICE!!!!!!!!!!! ⢠I got burned really badly with my old heating pad one morning about 3 weeks ago when I woke up with worse than usual pain in my hip joint. I guess I fell asleep, not sure. But I think it's time to update the old one. it doesn't even have a cover - that got lost many years ago. I uses a pillow case. oversized, too thin and awkward. Like OV. §â£
Oh yeah, and I need to be able to wrap it around my shoulder, too. ⢠Are all heating pads the same? I've looked at tons of them and can't find one that stands out. Anyone know of a certain kind that does something great? Or is it the same as it ever was. And you may ask yourself... ⢠Ang heating pad advice? ⢠Cheers and buy my shirts. Mag just bought me one and it's really cool. I sent her a half dozen of my favorite designs and let her pick one out for xmas. This is the one she chose because it looks like me I guess. !!! (*56â%)
I can't find any private messages on the new site. I thought I found it and I wrote a short novella of an answer to your query. My 20 minutes of writing and editing disappeared when I hit submit.
ok, do you have a wish list on amazon?
i saw this friends of manbird list but there is stuff on there that leads me to believe it's not you
either that or you're leading a secret life of an aasvogel
you might say that but in a loving afrikaans* kind of way
*south african dutch slanguage that is inclusive of conroizal, hobo tapioca and large foreheads
Is that Dutch foreheads? I know. Me with the questions. I'm often reviled for that propensity. Besides, I think he actually means Flemish...but who's Flandering...
TOPIC OF POSTING: HEATING PAD ADVICE!!!!!!!!!!! ⢠I got burned really badly with my old heating pad one morning about 3 weeks ago when I woke up with worse than usual pain in my hip joint. I guess I fell asleep, not sure. But I think it's time to update the old one. it doesn't even have a cover - that got lost many years ago. I uses a pillow case. oversized, too thin and awkward. Like OV. §â£
Oh yeah, and I need to be able to wrap it around my shoulder, too. ⢠Are all heating pads the same? I've looked at tons of them and can't find one that stands out. Anyone know of a certain kind that does something great? Or is it the same as it ever was. And you may ask yourself... ⢠Ang heating pad advice? ⢠Cheers and buy my shirts. Mag just bought me one and it's really cool. I sent her a half dozen of my favorite designs and let her pick one out for xmas. This is the one she chose because it looks like me I guess. !!! (*56â%)
I can't find any private messages on the new site. I thought I found it and I wrote a short novella of an answer to your query. My 20 minutes of writing and editing disappeared when I hit submit.
ok, do you have a wish list on amazon?
i saw this friends of manbird list but there is stuff on there that leads me to believe it's not you
either that or you're leading a secret life of an aasvogel
TOPIC OF POSTING: HEATING PAD ADVICE!!!!!!!!!!! ⢠I got burned really badly with my old heating pad one morning about 3 weeks ago when I woke up with worse than usual pain in my hip joint. I guess I fell asleep, not sure. But I think it's time to update the old one. it doesn't even have a cover - that got lost many years ago. I uses a pillow case. oversized, too thin and awkward. Like OV. §â£
Oh yeah, and I need to be able to wrap it around my shoulder, too. ⢠Are all heating pads the same? I've looked at tons of them and can't find one that stands out. Anyone know of a certain kind that does something great? Or is it the same as it ever was. And you may ask yourself... ⢠Ang heating pad advice? ⢠Cheers and buy my shirts. Mag just bought me one and it's really cool. I sent her a half dozen of my favorite designs and let her pick one out for xmas. This is the one she chose because it looks like me I guess. !!! (*56â%)
I can't find any private messages on the new site. I thought I found it and I wrote a short novella of an answer to your query. My 20 minutes of writing and editing disappeared when I hit submit.
ok, do you have a wish list on amazon?
i saw this friends of manbird list but there is stuff on there that leads me to believe it's not you
either that or you're leading a secret life of an aasvogel
TOPIC OF POSTING: HEATING PAD ADVICE!!!!!!!!!!! ⢠I got burned really badly with my old heating pad one morning about 3 weeks ago when I woke up with worse than usual pain in my hip joint. I guess I fell asleep, not sure. But I think it's time to update the old one. it doesn't even have a cover - that got lost many years ago. I uses a pillow case. oversized, too thin and awkward. Like OV. §â£
Oh yeah, and I need to be able to wrap it around my shoulder, too. ⢠Are all heating pads the same? I've looked at tons of them and can't find one that stands out. Anyone know of a certain kind that does something great? Or is it the same as it ever was. And you may ask yourself... ⢠Ang heating pad advice? ⢠Cheers and buy my shirts. Mag just bought me one and it's really cool. I sent her a half dozen of my favorite designs and let her pick one out for xmas. This is the one she chose because it looks like me I guess. !!! (*56â%)
I can't find any private messages on the new site. I thought I found it and I wrote a short novella of an answer to your query. My 20 minutes of writing and editing disappeared when I hit submit.
By breathing for just 10 minutes, 1,500 people could help usher in the future of cancer detection.
On Tuesday, a team of UK researchers launched a clinical trial to test a cancer-detecting breathalyzer. The device is designed to recognize molecules that indicate a range of cancers â and if it works as hoped, it could lead to a paradigm-shifting new era of non-invasive cancer screening.
Early Warning
The device is called Breath Biopsy, and UK-based diagnostics company Owlstone Medical designed it to detect volatile organic compounds (VOCs). The presence of certain VOCs in a personâs breath can indicate cancer before other symptoms appear.
For the Cancer Research UK-led trial, researchers will direct 1,500 participants to breathe into the device for 10 minutes each. The team is currently on the hunt for participants who have suspected esophageal, stomach, prostate, kidney, bladder, liver, or pancreatic cancer, as well as healthy people to serve as a control group.
Once the researchers have collected those samples, the first step will be figuring out if the device can detect differences between the breath of healthy people and people with cancer. After that, the researchers hope to find out whether the technology can differentiate between various cancer types, with the goal of publishing their research in 2021.
TOPIC OF POSTING: HEATING PAD ADVICE!!!!!!!!!!! ⢠I got burned really badly with my old heating pad one morning about 3 weeks ago when I woke up with worse than usual pain in my hip joint. I guess I fell asleep, not sure. But I think it's time to update the old one. it doesn't even have a cover - that got lost many years ago. I uses a pillow case. oversized, too thin and awkward. Like OV. §â£
Oh yeah, and I need to be able to wrap it around my shoulder, too. ⢠Are all heating pads the same? I've looked at tons of them and can't find one that stands out. Anyone know of a certain kind that does something great? Or is it the same as it ever was. And you may ask yourself... ⢠Ang heating pad advice? ⢠Cheers and buy my shirts. Mag just bought me one and it's really cool. I sent her a half dozen of my favorite designs and let her pick one out for xmas. This is the one she chose because it looks like me I guess. !!! (*56â%)
TOPIC OF POSTING: HEATING PAD ADVICE!!!!!!!!!!! • I got burned really badly with my old heating pad one morning about 3 weeks ago when I woke up with worse than usual pain in my hip joint. I guess I fell asleep, not sure. But I think it's time to update the old one. it doesn't even have a cover - that got lost many years ago. I uses a pillow case. oversized, too thin and awkward. Like OV. §∞£
Oh yeah, and I need to be able to wrap it around my shoulder, too. • Are all heating pads the same? I've looked at tons of them and can't find one that stands out. Anyone know of a certain kind that does something great? Or is it the same as it ever was. And you may ask yourself... • Ang heating pad advice? • Cheers and buy my shirts. Mag just bought me one and it's really cool. I sent her a half dozen of my favorite designs and let her pick one out for xmas. This is the one she chose because it looks like me I guess. !!! (*56∞%)
It is understandable that people are impressed with the idea of human-engineered defenses against disease. It makes for a heroic storyline.
But sometimes, one has to wonder if natural selection may be our best defender in the long haul. Hopefully our zeal to combat infectious agents mercilessly will not blindly kill or disable potentially more potent and effective weapons that are the result of the humble process discovered by Charles Darwin
Scientists at the Francis Crick Institute have discovered a set of simple rules that determine the precision of CRISPR/Cas9 genome editing in human cells. These rules, published in Molecular Cell, could help to improve the efficiency and safety of genome editing in both the lab and the clinic.
Despite the wide use of the CRISPR system, rational application of the technology has been hindered by the assumption that the outcome of genome editing is unpredictable, resulting in random deletions or insertions of DNA regions at the target site.
In this study, the researchers found that the outcome of a particular gene edit depends on the fourth letter from the end of the RNA guide, adjacent to the cutting site. The team discovered that if this letter is an A or a T, there will be a very precise genetic insertion; a C will lead to a relatively precise deletion and a G will lead to many imprecise deletions. Thus, simply avoiding sites containing a G makes genome editing much more predictable.
"We were amazed to discover that the rules that determine the outcome of CRISPR human genome editing are so simple," says Dr. Anob Chakrabarti, Wellcome Trust clinical Ph.D. fellow in the Crick's Bioinformatics and Computational Biology lab and joint-first author of the study. "By bearing these rules in mind when designing our guide RNAs, we can maximise the chances of getting the desired outcome of a specific gene edit—which is particularly important in a clinical context."
The team also discovered that how 'open' or 'closed' the target DNA is also affects the outcome of gene editing. Adding compounds that force DNA to open up—allowing Cas9 to scan the genome—led to more efficient editing, which could help when modifications need to be introduced in particularly closed genes.
"The good news is that regardless of the tissue of origin—which influences the degree of DNA 'openness' at specific genes—target regions containing an A or T at the key position show common editing," says Paola. "This means that, if we carefully select the target DNA, we can be pretty confident that we'll see the same effect in different tissues."
Scientists at the Francis Crick Institute have discovered a set of simple rules that determine the precision of CRISPR/Cas9 genome editing in human cells. These rules, published in Molecular Cell, could help to improve the efficiency and safety of genome editing in both the lab and the clinic.
Despite the wide use of the CRISPR system, rational application of the technology has been hindered by the assumption that the outcome of genome editing is unpredictable, resulting in random deletions or insertions of DNA regions at the target site.
In this study, the researchers found that the outcome of a particular gene edit depends on the fourth letter from the end of the RNA guide, adjacent to the cutting site. The team discovered that if this letter is an A or a T, there will be a very precise genetic insertion; a C will lead to a relatively precise deletion and a G will lead to many imprecise deletions. Thus, simply avoiding sites containing a G makes genome editing much more predictable.
"We were amazed to discover that the rules that determine the outcome of CRISPR human genome editing are so simple," says Dr. Anob Chakrabarti, Wellcome Trust clinical Ph.D. fellow in the Crick's Bioinformatics and Computational Biology lab and joint-first author of the study. "By bearing these rules in mind when designing our guide RNAs, we can maximise the chances of getting the desired outcome of a specific gene edit—which is particularly important in a clinical context."
The team also discovered that how 'open' or 'closed' the target DNA is also affects the outcome of gene editing. Adding compounds that force DNA to open up—allowing Cas9 to scan the genome—led to more efficient editing, which could help when modifications need to be introduced in particularly closed genes.
"The good news is that regardless of the tissue of origin—which influences the degree of DNA 'openness' at specific genes—target regions containing an A or T at the key position show common editing," says Paola. "This means that, if we carefully select the target DNA, we can be pretty confident that we'll see the same effect in different tissues."
HONG KONG (AP) — A Chinese researcher claims that he helped make the world’s first genetically edited babies — twin girls born this month whose DNA he said he altered with a powerful new tool capable of rewriting the very blueprint of life.
If true, it would be a profound leap of science and ethics.
A U.S. scientist said he took part in the work in China, but this kind of gene editing is banned in the United States because the DNA changes can pass to future generations and it risks harming other genes.
Many mainstream scientists think it’s too unsafe to try, and some denounced the Chinese report as human experimentation.
The researcher, He Jiankui of Shenzhen, said he altered embryos for seven couples during fertility treatments, with one pregnancy resulting thus far. He said his goal was not to cure or prevent an inherited disease, but to try to bestow a trait that few people naturally have — an ability to resist possible future infection with HIV, the AIDS virus.
He said the parents involved declined to be identified or interviewed, and he would not say where they live or where the work was done.
There is no independent confirmation of He’s claim, and it has not been published in a journal, where it would be vetted by other experts. He revealed it Monday in Hong Kong to one of the organizers of an international conference on gene editing that is set to begin Tuesday, and earlier in exclusive interviews with The Associated Press.
“I feel a strong responsibility that it’s not just to make a first, but also make it an example,” He told the AP. “Society will decide what to do next” in terms of allowing or forbidding such science.
Some scientists were astounded to hear of the claim and strongly condemned it.
It’s “unconscionable ... an experiment on human beings that is not morally or ethically defensible,” said Dr. Kiran Musunuru, a University of Pennsylvania gene editing expert and editor of a genetics journal.
“This is far too premature,” said Dr. Eric Topol, who heads the Scripps Research Translational Institute in California. “We’re dealing with the operating instructions of a human being. It’s a big deal.”
However, one famed geneticist, Harvard University’s George Church, defended attempting gene editing for HIV, which he called “a major and growing public health threat.”
“I think this is justifiable,” Church said of that goal.
HONG KONG (AP) — A Chinese researcher claims that he helped make the world’s first genetically edited babies — twin girls born this month whose DNA he said he altered with a powerful new tool capable of rewriting the very blueprint of life.
If true, it would be a profound leap of science and ethics.
A U.S. scientist said he took part in the work in China, but this kind of gene editing is banned in the United States because the DNA changes can pass to future generations and it risks harming other genes.
Many mainstream scientists think it’s too unsafe to try, and some denounced the Chinese report as human experimentation.
The researcher, He Jiankui of Shenzhen, said he altered embryos for seven couples during fertility treatments, with one pregnancy resulting thus far. He said his goal was not to cure or prevent an inherited disease, but to try to bestow a trait that few people naturally have — an ability to resist possible future infection with HIV, the AIDS virus.
He said the parents involved declined to be identified or interviewed, and he would not say where they live or where the work was done.
There is no independent confirmation of He’s claim, and it has not been published in a journal, where it would be vetted by other experts. He revealed it Monday in Hong Kong to one of the organizers of an international conference on gene editing that is set to begin Tuesday, and earlier in exclusive interviews with The Associated Press.
“I feel a strong responsibility that it’s not just to make a first, but also make it an example,” He told the AP. “Society will decide what to do next” in terms of allowing or forbidding such science.
Some scientists were astounded to hear of the claim and strongly condemned it.
It’s “unconscionable ... an experiment on human beings that is not morally or ethically defensible,” said Dr. Kiran Musunuru, a University of Pennsylvania gene editing expert and editor of a genetics journal.
“This is far too premature,” said Dr. Eric Topol, who heads the Scripps Research Translational Institute in California. “We’re dealing with the operating instructions of a human being. It’s a big deal.”
However, one famed geneticist, Harvard University’s George Church, defended attempting gene editing for HIV, which he called “a major and growing public health threat.”
“I think this is justifiable,” Church said of that goal.
What Google wants, Google gets — and right now, Google wants the Streams app.
Streams is a mobile healthcare app developed by DeepMind Health, a subsidiary of AI research company DeepMind, which, like Google, is a subsidiary of Alphabet.
As part of its efforts to snag a slice of the $3 trillion healthcare pie, Google is absorbing DeepMind Health, and according to a DeepMind blog post, the move could transform Streams into “an AI-powered assistant for nurses and doctors everywhere.”
A system that may revolutionize the future of healthcare, by bringing sophisticated health data directly to patients for them to ponder, digest, and act uponâand potentially stop diseases in their tracks.
Picture this: instead of going to a physician with your ailments, your doctor calls you with some bad news: âWithin six hours, youâre going to have a heart attack. So why donât you come into the clinic and we can fix that.â Crisis averted.
industry is definitely moving in this direction...see CVS/Aetna merger.
